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Synthetic Toll-Like Receptor 4 (TLR4) and TLR7 Ligands Work Additively via MyD88 To Induce Protective Antiviral Immunity in Mice

We previously demonstrated that the combination of synthetic small-molecule Toll-like receptor 4 (TLR4) and TLR7 ligands is a potent adjuvant for recombinant influenza virus hemagglutinin, inducing rapid and sustained immunity that is protective against influenza viruses in homologous, heterologous,...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Goff, Peter H., Hayashi, Tomoko, He, Wenqian, Yao, Shiyin, Cottam, Howard B., Tan, Gene S., Crain, Brian, Krammer, Florian, Messer, Karen, Pu, Minya, Carson, Dennis A., Palese, Peter, Corr, Maripat
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599744/
https://ncbi.nlm.nih.gov/pubmed/28724768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01050-17
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