Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques

Evaluation of the epitope specificities, locations (systemic or mucosal), and effector functions of antibodies elicited by novel HIV-1 immunogens engineered to improve exposure of specific epitopes is critical for HIV-1 vaccine development. Utilizing an array of humoral assays, we evaluated the magn...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Shen, Xiaoying, Bogers, Willy M., Yates, Nicole L., Ferrari, Guido, Dey, Antu K., Williams, William T., Jaeger, Frederick H., Wiehe, Kevin, Sawant, Sheetal, Alam, S. Munir, LaBranche, Celia C., Montefiori, David C., Martin, Loic, Srivastava, Indresh, Heeney, Jonathan, Barnett, Susan W., Tomaras, Georgia D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599731/
https://ncbi.nlm.nih.gov/pubmed/28490585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00401-17
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge