Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques

Evaluation of the epitope specificities, locations (systemic or mucosal), and effector functions of antibodies elicited by novel HIV-1 immunogens engineered to improve exposure of specific epitopes is critical for HIV-1 vaccine development. Utilizing an array of humoral assays, we evaluated the magn...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Shen, Xiaoying, Bogers, Willy M., Yates, Nicole L., Ferrari, Guido, Dey, Antu K., Williams, William T., Jaeger, Frederick H., Wiehe, Kevin, Sawant, Sheetal, Alam, S. Munir, LaBranche, Celia C., Montefiori, David C., Martin, Loic, Srivastava, Indresh, Heeney, Jonathan, Barnett, Susan W., Tomaras, Georgia D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Vaccines and Antiviral Agents
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599731/
https://ncbi.nlm.nih.gov/pubmed/28490585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00401-17
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