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Phosphorylation of the C-Raf N Region Promotes Raf Dimerization
The activation of Raf kinases by the small GTPase Ras requires two major sets of phosphorylations. One set lies within the activation loop, and the other lies within the N-terminal acidic region (N region). In the most abundant isoform of Raf, C-Raf, N-region phosphorylations occur on serine 338 (S3...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599720/ https://ncbi.nlm.nih.gov/pubmed/28694330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00132-17 |
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