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Novel insight into streptozotocin-induced diabetic rats from the protein misfolding perspective

Protein folding is a process of self-assembly defined by the sequence of the amino acids of the protein involved. Additionally, proteins tend to unfold, misfold and aggregate due to both intrinsic and extrinsic causes. Human islet amyloid polypeptide (hIAPP) aggregation is an early step in diabetes...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Leyva-García, Edgar, Lara-Martínez, Reyna, Morán-Zanabria, Liborio, Revilla-Monsalve, Cristina, Jiménez-García, Luis Felipe, Oviedo, Norma, Murata, Chiharu, Garrido-Magaña, Eulalia, Altamirano-Bustamante, Nelly F., Altamirano-Bustamante, Myriam M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599686/
https://ncbi.nlm.nih.gov/pubmed/28912603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11776-y
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