A Novel Interaction of PAK4 with PPARγ to Regulate Nox1 and Radiation-Induced Epithelial-to-Mesenchymal Transition in Glioma

Tumor recurrence in glioblastoma (GBM) is, in part, attributed to increased epithelial-to-mesenchymal transition (EMT) and enhanced tumor cell dissemination in adjacent brain parenchyma after ionizing radiation (IR). EMT is associated with aggressive behavior, increased stem-like characteristics and...

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Publicado en:Oncogene
Autores principales: Kesanakurti, Divya, Maddirela, Dilip, Mohanam, Sanjeeva, Kaur, Balveen, Puduvalli, Vinay K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599308/
https://ncbi.nlm.nih.gov/pubmed/28534509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.261
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