Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma

Gliomas display anoikis resistance, enhanced invasion in to the adjacent brain parenchyma and eventually recur despite using the standard therapies. Our studies on increased anoikis sensitization in matrix metalloproteinase-2 (MMP-2)-knockdown 4910 and 5310 human glioma xenograft cells were interest...

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Detalhes bibliográficos
Main Authors: Kesanakurti, D, Chetty, C, Rajasekhar Maddirela, D, Gujrati, M, Rao, J S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542618/
https://ncbi.nlm.nih.gov/pubmed/23254288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.182
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