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Role of MMP-2 in the Regulation of IL-6/Stat3 Survival Signaling via Interaction With α5β1 Integrin in glioma
MMP-2 plays pivotal role in the degradation of extracellular matrix, and thereby enhances the invasive, proliferative and metastatic potential in cancer. Knockdown of MMP-2 using MMP-2 siRNA (pM) in human glioma xenograft cell lines 4910 and 5310 decreased cell proliferation compared to mock- and pS...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368064/ https://ncbi.nlm.nih.gov/pubmed/22349830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.52 |
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