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Essential Role of Cooperative NF-κB and Stat3 Recruitment to ICAM-1 Intronic Consensus Elements in the Regulation of Radiation-induced Invasion and Migration in Glioma

Although radiotherapy improves survival in patients, GBMs tend to relapse with augmented tumor migration and invasion even after irradiation (IR). Aberrant NF-κB and Stat3 activation and interaction has been suggested in several human tumors. However, possible NF-κB/Stat3 interaction and the role of...

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Bibliographic Details
Main Authors: Kesanakurti, Divya, Chetty, Chandramu, Maddirela, Dilip Rajasekhar, Gujrati, Meena, Rao, Jasti S.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664652/
https://ncbi.nlm.nih.gov/pubmed/23178493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.546
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