Role of MMP-2 in the Regulation of IL-6/Stat3 Survival Signaling via Interaction With α5β1 Integrin in glioma

MMP-2 plays pivotal role in the degradation of extracellular matrix, and thereby enhances the invasive, proliferative and metastatic potential in cancer. Knockdown of MMP-2 using MMP-2 siRNA (pM) in human glioma xenograft cell lines 4910 and 5310 decreased cell proliferation compared to mock- and pS...

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Hauptverfasser: Kesanakurti, Divya, Chetty, Chandramu, Dinh, Dzung H., Gujrati, Meena, Rao, Jasti S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368064/
https://ncbi.nlm.nih.gov/pubmed/22349830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.52
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