Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma

Gliomas display anoikis resistance, enhanced invasion in to the adjacent brain parenchyma and eventually recur despite using the standard therapies. Our studies on increased anoikis sensitization in matrix metalloproteinase-2 (MMP-2)-knockdown 4910 and 5310 human glioma xenograft cells were interest...

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Main Authors: Kesanakurti, D, Chetty, C, Rajasekhar Maddirela, D, Gujrati, M, Rao, J S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542618/
https://ncbi.nlm.nih.gov/pubmed/23254288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.182
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