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Polygenic Risk Score Analysis of Pathologically Confirmed Alzheimer's Disease

Previous estimates of the utility of polygenic risk score analysis for the prediction of Alzheimer's disease have given Area Under the Curve estimates of <80%. However, these have been based on the genetic analysis of clinical case control series. Here we apply the same analytic approaches t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ann Neurol
Prif Awduron: Escott-Price, Valentina, Myers, Amanda J., Huentelman, Matt, Hardy, John
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599118/
https://ncbi.nlm.nih.gov/pubmed/28727176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24999
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