Wird geladen...
Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cells
Sepsis is a systemic infection that enhances host vulnerability to secondary infections normally controlled by T cells. Using CLP sepsis model, we observed that sepsis induces apoptosis of circulating memory CD8 T-cells (T(CIRCM)) and diminishes their effector functions, leading to impaired CD8 T-ce...
Gespeichert in:
| Veröffentlicht in: | PLoS Pathog |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2017
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599054/ https://ncbi.nlm.nih.gov/pubmed/28910403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006569 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|