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Polymicrobial Sepsis Diminishes Dendritic Cell Numbers and Function Directly Contributing to Impaired Primary CD8 T-Cell Responses in vivo()
Patients surviving acute stages of sepsis often display impaired adaptive immune responses. Using the cecal ligation and puncture (CLP) model, we demonstrated that sepsis leads to substantial and long-lasting changes in the naïve CD8 T-cell repertoire affecting the capacity of the host to respond to...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5123856/ https://ncbi.nlm.nih.gov/pubmed/27798171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601463 |
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