More Dose-dependent Side Effects with Mercaptopurine over Azathioprine in IBD Treatment Due to Relatively Higher Dosing

BACKGROUND: There are substantial global differences in the preference for mercaptopurine (MP) or its prodrug azathioprine (AZA) as first-choice thiopurine to treat inflammatory bowel diseases. Studies comparing both agents are scarce. Our aim was to compare AZA and MP in thiopurine-naive patients w...

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Pubblicato in:Inflamm Bowel Dis
Autori principali: Broekman, Mark M. T. J., Coenen, Marieke J. H., van Marrewijk, Corine J., Wanten, Geert J. A., Wong, Dennis R., Verbeek, Andre L. M., Klungel, Olaf H., Hooymans, Piet M., Guchelaar, Henk-Jan, Scheffer, Hans, Derijks, Luc J. J., de Jong, Dirk J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2017
Soggetti:
Original Clinical Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598908/
https://ncbi.nlm.nih.gov/pubmed/28644183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000001163
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