More Dose-dependent Side Effects with Mercaptopurine over Azathioprine in IBD Treatment Due to Relatively Higher Dosing

BACKGROUND: There are substantial global differences in the preference for mercaptopurine (MP) or its prodrug azathioprine (AZA) as first-choice thiopurine to treat inflammatory bowel diseases. Studies comparing both agents are scarce. Our aim was to compare AZA and MP in thiopurine-naive patients w...

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Publicado en:Inflamm Bowel Dis
Autores principales: Broekman, Mark M. T. J., Coenen, Marieke J. H., van Marrewijk, Corine J., Wanten, Geert J. A., Wong, Dennis R., Verbeek, Andre L. M., Klungel, Olaf H., Hooymans, Piet M., Guchelaar, Henk-Jan, Scheffer, Hans, Derijks, Luc J. J., de Jong, Dirk J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Original Clinical Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598908/
https://ncbi.nlm.nih.gov/pubmed/28644183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000001163
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