More Dose-dependent Side Effects with Mercaptopurine over Azathioprine in IBD Treatment Due to Relatively Higher Dosing

BACKGROUND: There are substantial global differences in the preference for mercaptopurine (MP) or its prodrug azathioprine (AZA) as first-choice thiopurine to treat inflammatory bowel diseases. Studies comparing both agents are scarce. Our aim was to compare AZA and MP in thiopurine-naive patients w...

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Vydáno v:Inflamm Bowel Dis
Hlavní autoři: Broekman, Mark M. T. J., Coenen, Marieke J. H., van Marrewijk, Corine J., Wanten, Geert J. A., Wong, Dennis R., Verbeek, Andre L. M., Klungel, Olaf H., Hooymans, Piet M., Guchelaar, Henk-Jan, Scheffer, Hans, Derijks, Luc J. J., de Jong, Dirk J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2017
Témata:
Original Clinical Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598908/
https://ncbi.nlm.nih.gov/pubmed/28644183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000001163
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