Genotype-Guided Thiopurine Dosing Does not Lead to Additional Costs in Patients With Inflammatory Bowel Disease

BACKGROUND AND AIMS: Decreased thiopurine S-methyltransferase [TPMT] enzyme activity increases the risk of haematological adverse drug reactions [ADRs] in patients treated with thiopurines. Clinical studies have shown that in patients with inflammatory bowel disease [IBD], pharmacogenetic TPMT-guide...

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Bibliografske podrobnosti
izdano v:J Crohns Colitis
Main Authors: Sluiter, Reinier L, van Marrewijk, Corine, de Jong, Dirk, Scheffer, Hans, Guchelaar, Henk-Jan, Derijks, Luc, Wong, Dennis R, Hooymans, Piet, Vermeulen, Sita H, Verbeek, André L M, Franke, Barbara, van der Wilt, Gert Jan, Kievit, Wietske, Coenen, Marieke J H
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142326/
https://ncbi.nlm.nih.gov/pubmed/30698675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjz009
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