More Dose-dependent Side Effects with Mercaptopurine over Azathioprine in IBD Treatment Due to Relatively Higher Dosing

BACKGROUND: There are substantial global differences in the preference for mercaptopurine (MP) or its prodrug azathioprine (AZA) as first-choice thiopurine to treat inflammatory bowel diseases. Studies comparing both agents are scarce. Our aim was to compare AZA and MP in thiopurine-naive patients w...

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Détails bibliographiques
Publié dans:Inflamm Bowel Dis
Auteurs principaux: Broekman, Mark M. T. J., Coenen, Marieke J. H., van Marrewijk, Corine J., Wanten, Geert J. A., Wong, Dennis R., Verbeek, Andre L. M., Klungel, Olaf H., Hooymans, Piet M., Guchelaar, Henk-Jan, Scheffer, Hans, Derijks, Luc J. J., de Jong, Dirk J.
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2017
Sujets:
Original Clinical Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598908/
https://ncbi.nlm.nih.gov/pubmed/28644183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000001163
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