Interferon-γ treatment in vitro elicits some of the changes in cathepsin S and antigen presentation characteristic of lacrimal glands and corneas from the NOD mouse model of Sjögren’s Syndrome

Inflammation and impaired secretion by lacrimal and salivary glands are hallmarks of the autoimmune disease, Sjögren’s Syndrome. These changes in the lacrimal gland promote dryness and inflammation of the ocular surface, causing pain, irritation and corneal damage. The changes that initiate and sust...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Meng, Zhen, Klinngam, Wannita, Edman, Maria C., Hamm-Alvarez, Sarah F.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597228/
https://ncbi.nlm.nih.gov/pubmed/28902875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184781
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