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Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome

The mechanism responsible for the altered spectrum of tear proteins secreted by lacrimal gland acinar cells (LGAC) in patients with Sjögren's Syndrome (SS) remains unknown. We have previously identified increased cathepsin S (CTSS) activity as a unique characteristic of tears of patients with S...

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Publicat a:Am J Physiol Cell Physiol
Autors principals: Meng, Zhen, Edman, Maria C., Hsueh, Pang-Yu, Chen, Chiao-Yu, Klinngam, Wannita, Tolmachova, Tanya, Okamoto, Curtis T., Hamm-Alvarez, Sarah F.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935202/
https://ncbi.nlm.nih.gov/pubmed/27076615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00275.2015
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