Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome

The mechanism responsible for the altered spectrum of tear proteins secreted by lacrimal gland acinar cells (LGAC) in patients with Sjögren's Syndrome (SS) remains unknown. We have previously identified increased cathepsin S (CTSS) activity as a unique characteristic of tears of patients with S...

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Veröffentlicht in:Am J Physiol Cell Physiol
Hauptverfasser: Meng, Zhen, Edman, Maria C., Hsueh, Pang-Yu, Chen, Chiao-Yu, Klinngam, Wannita, Tolmachova, Tanya, Okamoto, Curtis T., Hamm-Alvarez, Sarah F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2016
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935202/
https://ncbi.nlm.nih.gov/pubmed/27076615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00275.2015
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