Interferon-γ treatment in vitro elicits some of the changes in cathepsin S and antigen presentation characteristic of lacrimal glands and corneas from the NOD mouse model of Sjögren’s Syndrome

Inflammation and impaired secretion by lacrimal and salivary glands are hallmarks of the autoimmune disease, Sjögren’s Syndrome. These changes in the lacrimal gland promote dryness and inflammation of the ocular surface, causing pain, irritation and corneal damage. The changes that initiate and sust...

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Vydáno v:PLoS One
Hlavní autoři: Meng, Zhen, Klinngam, Wannita, Edman, Maria C., Hamm-Alvarez, Sarah F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597228/
https://ncbi.nlm.nih.gov/pubmed/28902875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184781
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