Interferon-γ treatment in vitro elicits some of the changes in cathepsin S and antigen presentation characteristic of lacrimal glands and corneas from the NOD mouse model of Sjögren’s Syndrome

Inflammation and impaired secretion by lacrimal and salivary glands are hallmarks of the autoimmune disease, Sjögren’s Syndrome. These changes in the lacrimal gland promote dryness and inflammation of the ocular surface, causing pain, irritation and corneal damage. The changes that initiate and sust...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Meng, Zhen, Klinngam, Wannita, Edman, Maria C., Hamm-Alvarez, Sarah F.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597228/
https://ncbi.nlm.nih.gov/pubmed/28902875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184781
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items