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Sirtuin Lipoamidase Activity Is Conserved in Bacteria as a Regulator of Metabolic Enzyme Complexes

Lipoic acid is an essential metabolic cofactor added as a posttranslational modification on several multimeric enzyme complexes. These protein complexes, evolutionarily conserved from bacteria to humans, are core regulators of cellular metabolism. While the multistep enzymatic process of adding lipo...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Rowland, Elizabeth A., Greco, Todd M., Snowden, Caroline K., McCabe, Anne L., Silhavy, Thomas J., Cristea, Ileana M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596343/
https://ncbi.nlm.nih.gov/pubmed/28900027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01096-17
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