Sirtuins Are Evolutionarily Conserved Viral Restriction Factors

The seven human sirtuins are a family of ubiquitously expressed and evolutionarily conserved NAD(+)-dependent deacylases/mono-ADP ribosyltransferases that regulate numerous cellular and organismal functions, including metabolism, cell cycle, and longevity. Here, we report the discovery that all seve...

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Pubblicato in:mBio
Autori principali: Koyuncu, Emre, Budayeva, Hanna G., Miteva, Yana V., Ricci, Dante P., Silhavy, Thomas J., Shenk, Thomas, Cristea, Ileana M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Microbiology 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271551/
https://ncbi.nlm.nih.gov/pubmed/25516616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02249-14
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