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Human Sirtuin 2 Localization, Transient Interactions, and Impact on the Proteome Point to Its Role in Intracellular Trafficking
Human sirtuin 2 (SIRT2) is an NAD(+)-dependent deacetylase that primarily functions in the cytoplasm, where it can regulate α-tubulin acetylation levels. SIRT2 is linked to cancer progression, neurodegeneration, and infection with bacteria or viruses. However, the current knowledge about its interac...
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| Yayımlandı: | Mol Cell Proteomics |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The American Society for Biochemistry and Molecular Biology
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5054338/ https://ncbi.nlm.nih.gov/pubmed/27503897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.061333 |
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