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Dosimetry and first human experience with (89)Zr-panitumumab

(89)Zr-panitumumab is a novel immuno-PET radiotracer. A fully humanized IgG2 antibody, panitumumab binds with high affinity to the extracellular ligand binding domain of EGFR. Immuno-PET with radiolabeled panitumumab is a non-invasive method that could characterize EGFR expression in tumors and meta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Am J Nucl Med Mol Imaging
Hauptverfasser: Lindenberg, Liza, Adler, Stephen, Turkbey, Ismail B, Mertan, Francesca, Ton, Anita, Do, Khanh, Kummar, Shivaani, Gonzalez, Esther Mena, Bhattacharyya, Sibaprasad, Jacobs, Paula M, Choyke, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596322/
https://ncbi.nlm.nih.gov/pubmed/28913158
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