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Preparation of clinical-grade (89)Zr-panitumumab as a positron emission tomography biomarker for evaluating epidermal growth factor receptor-targeted therapy

Panitumumab is a fully human monoclonal antibody approved for the treatment of epidermal growth factor receptor (EGFR) positive colorectal cancer. Recently, panitumumab has been radiolabeled with (89)Zr and evaluated for its potential to be used as immuno-positron emission tomography (PET) probe for...

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Autori principali: Wei, Ling, Shi, Jianfeng, Afari, George, Bhattacharyya, Sibaprasad
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982615/
https://ncbi.nlm.nih.gov/pubmed/24448743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3134
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