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Development and Characterization of (89)Zr-Labeled Panitumumab for Immuno–Positron Emission Tomographic Imaging of the Epidermal Growth Factor Receptor

The epidermal growth factor receptor (EGFR) is overexpressed in the majority of malignancies and has been associated with poor outcomes. Panitumumab, an anti-EGFR monoclonal antibody that binds to the extracellular binding domain of EGFR, is increasingly used with radiotherapy and chemotherapy but h...

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Détails bibliographiques
Publié dans:Mol Imaging
Auteurs principaux: Chang, Albert J., De Silva, Ravindra A., Lapi, Suzanne E.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329987/
https://ncbi.nlm.nih.gov/pubmed/23348788
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