(89)Zr-Radiolabeled Trastuzumab Imaging in Orthotopic and Metastatic Breast Tumors

The human epidermal growth factor receptor 2 (HER2/neu) is overexpressed in 20–30% of breast cancers and is associated with tumor growth, angiogenesis, and development of distant metastases. Trastuzumab, an anti-HER2 monoclonal antibody, is used for the treatment of HER2 positive breast cancer and c...

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Hauptverfasser: Chang, Albert J., DeSilva, Ravindra, Jain, Sandeep, Lears, Kimberley, Rogers, Buck, Lapi, Suzanne
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763623/
https://ncbi.nlm.nih.gov/pubmed/24288044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph5010079
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