Zirconium-89 Labeled Panitumumab: a Potential Immuno-PET Probe for HER1-Expressing Carcinomas

INTRODUCTION: Anti-HER1 monoclonal antibody (mAb), panitumumab (Vectibix®) is a fully human mAb approved by the FDA for the treatment of epidermal growth factor receptor (EGFR, HER1)-expressing colorectal cancers. By combining the targeted specificity of panitumumab with the quantitative in vivo ima...

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Autors principals: Bhattacharyya, Sibaprasad, Kurdziel, Karen, Wei, Ling, Riffle, Lisa, Kaur, Gurmeet, Hill, G. Craig, Jacobs, Paula M., Tatum, James L., Doroshow, James H., Kalen, Joseph D.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637856/
https://ncbi.nlm.nih.gov/pubmed/23454247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2013.01.007
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