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Synthesis and biological evaluation of panitumumab-IRDye800 conjugate as a fluorescence imaging probe for EGFR-expressing cancers

To investigate panitumumab-IRDye800 as an intraoperative optical imaging agent for epidermal growth factor receptor (EGFR)-expressing cancers, we developed clinical-quality panitumumab-IRDye800 and evaluated its specificity and sensitivity to visualize tumors by fluorescence imaging in a variety of...

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Detalles Bibliográficos
Publicado en:Medchemcomm
Main Authors: Bhattacharyya, Sibaprasad, Patel, Nimit, Wei, Ling, Riffle, Lisa A., Kalen, Joseph D., Hill, G. Craig, Jacobs, Paula M., Zinn, Kurt R., Rosenthal, Eben
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241857/
https://ncbi.nlm.nih.gov/pubmed/25431648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4MD00116H
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