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Serpine 1 induces alveolar type II cell senescence through activating p53‐p21‐Rb pathway in fibrotic lung disease

Senescence of alveolar type 2 (ATII) cells, progenitors of the alveolar epithelium, is implicated in the pathogeneses of idiopathic pulmonary fibrosis (IPF), an aging‐related progressive fatal lung disorder with unknown etiology. The mechanism underlying ATII cell senescence in fibrotic lung disease...

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書目詳細資料
發表在:Aging Cell
Main Authors: Jiang, Chunsun, Liu, Gang, Luckhardt, Tracy, Antony, Veena, Zhou, Yong, Carter, A. Brent, Thannickal, Victor J., Liu, Rui‐Ming
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595683/
https://ncbi.nlm.nih.gov/pubmed/28722352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12643
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