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ICG-001 suppresses growth of gastric cancer cells and reduces chemoresistance of cancer stem cell-like population
BACKGROUND: ICG-001, a small molecule, binds CREB-binding protein (CBP) to disrupt its interaction with β-catenin and inhibits CBP function as a co-activator of Wnt/β-catenin-mediated transcription. Given its ability to inhibit Wnt/β-catenin signaling pathway, ICG-001 has been used in some tumor typ...
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| Udgivet i: | J Exp Clin Cancer Res |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5594604/ https://ncbi.nlm.nih.gov/pubmed/28893318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0595-0 |
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