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Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells

BACKGROUND: Cisplatin-based chemotherapy is frequently used to treat advanced gastric cancer (GC). However, the resistance often occurs with the mechanisms being not well understood. Recently, emerging evidence indicates that tumor-associated macrophages (TAMs) play an important role in chemoresista...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Zheng, Peiming, Chen, Lei, Yuan, Xiangliang, Luo, Qin, Liu, Yi, Xie, Guohua, Ma, Yanhui, Shen, Lisong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390430/
https://ncbi.nlm.nih.gov/pubmed/28407783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0528-y
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