CD19(+)CD24(hi)CD38(hi)Bregs involved in downregulate helper T cells and upregulate regulatory T cells in gastric cancer

Regulatory B cells (Bregs) play a critical role in inflammation and autoimmune disease. We characterized the role of Bregs in the progression of gastric cancer. We detected an increase in Bregs producing IL-10 both in peripheral blood mononuclear cells (PBMCs) and in gastric tumors. Multicolor flow...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Weiwei, Yuan, Xiangliang, Chen, Hui, Xie, Guohua, Ma, Yanhui, Zheng, Yingxia, Zhou, Yunlan, Shen, Lisong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741780/
https://ncbi.nlm.nih.gov/pubmed/26378021
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