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CD19(+)CD24(hi)CD38(hi)Bregs involved in downregulate helper T cells and upregulate regulatory T cells in gastric cancer
Regulatory B cells (Bregs) play a critical role in inflammation and autoimmune disease. We characterized the role of Bregs in the progression of gastric cancer. We detected an increase in Bregs producing IL-10 both in peripheral blood mononuclear cells (PBMCs) and in gastric tumors. Multicolor flow...
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| Veröffentlicht in: | Oncotarget |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4741780/ https://ncbi.nlm.nih.gov/pubmed/26378021 |
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