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Pharmacological targeting of peptidylarginine deiminase 4 prevents cancer-associated kidney injury in mice

Renal insufficiency is a frequent cancer-associated problem affecting more than half of all cancer patients at the time of diagnosis. To minimize nephrotoxic effects the dosage of anticancer drugs are reduced in these patients, leading to sub-optimal treatment efficacy. Despite the severity of this...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Cedervall, Jessica, Dragomir, Anca, Saupe, Falk, Zhang, Yanyu, Ärnlöv, Johan, Larsson, Erik, Dimberg, Anna, Larsson, Anders, Olsson, Anna-Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593702/
https://ncbi.nlm.nih.gov/pubmed/28919990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1320009
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