Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice

Protein citrullination plays a role in several autoimmune diseases. Its involvement in murine and human type 1 diabetes has recently been recognized through the discovery of antibodies and T-cell reactivity against citrullinated peptides. In the current study, we demonstrate that systemic inhibition...

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Detaylı Bibliyografya
Yayımlandı:Diabetes
Asıl Yazarlar: Sodré, Fernanda M.C., Bissenova, Samal, Bruggeman, Ylke, Tilvawala, Ronak, Cook, Dana P., Berthault, Claire, Mondal, Santanu, Callebaut, Aïsha, You, Sylvaine, Scharfmann, Raphael, Mallone, Roberto, Thompson, Paul R., Mathieu, Chantal, Buitinga, Mijke, Overbergh, Lut
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2021
Konular:
Immunology and Transplantation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881854/
https://ncbi.nlm.nih.gov/pubmed/33203696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0421
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