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Pharmacological targeting of peptidylarginine deiminase 4 prevents cancer-associated kidney injury in mice

Renal insufficiency is a frequent cancer-associated problem affecting more than half of all cancer patients at the time of diagnosis. To minimize nephrotoxic effects the dosage of anticancer drugs are reduced in these patients, leading to sub-optimal treatment efficacy. Despite the severity of this...

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Vydáno v:Oncoimmunology
Hlavní autoři: Cedervall, Jessica, Dragomir, Anca, Saupe, Falk, Zhang, Yanyu, Ärnlöv, Johan, Larsson, Erik, Dimberg, Anna, Larsson, Anders, Olsson, Anna-Karin
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593702/
https://ncbi.nlm.nih.gov/pubmed/28919990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1320009
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