Pharmacological targeting of peptidylarginine deiminase 4 prevents cancer-associated kidney injury in mice

Renal insufficiency is a frequent cancer-associated problem affecting more than half of all cancer patients at the time of diagnosis. To minimize nephrotoxic effects the dosage of anticancer drugs are reduced in these patients, leading to sub-optimal treatment efficacy. Despite the severity of this...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Cedervall, Jessica, Dragomir, Anca, Saupe, Falk, Zhang, Yanyu, Ärnlöv, Johan, Larsson, Erik, Dimberg, Anna, Larsson, Anders, Olsson, Anna-Karin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593702/
https://ncbi.nlm.nih.gov/pubmed/28919990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1320009
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