Molecular and functional characterization of a new 3′ end KIT juxtamembrane deletion in a duodenal GIST treated with neoadjuvant Imatinib

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. GISTs express the receptor tyrosine kinase KIT, and the majority of GISTs present KIT gain-of-function mutations that cluster in the 5′ end of the receptor juxtamembrane domain. On the other...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Perfetti, Vittorio, Laurini, Erik, Aulić, Suzana, Fermeglia, Maurizio, Riboni, Roberta, Lucioni, Marco, Dallera, Elena, Delfanti, Sara, Pugliese, Luigi, Latteri, Francesco Saverio, Pietrabissa, Andrea, Pricl, Sabrina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593551/
https://ncbi.nlm.nih.gov/pubmed/28915580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19341
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