Molecular and functional characterization of a new 3′ end KIT juxtamembrane deletion in a duodenal GIST treated with neoadjuvant Imatinib

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. GISTs express the receptor tyrosine kinase KIT, and the majority of GISTs present KIT gain-of-function mutations that cluster in the 5′ end of the receptor juxtamembrane domain. On the other...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Perfetti, Vittorio, Laurini, Erik, Aulić, Suzana, Fermeglia, Maurizio, Riboni, Roberta, Lucioni, Marco, Dallera, Elena, Delfanti, Sara, Pugliese, Luigi, Latteri, Francesco Saverio, Pietrabissa, Andrea, Pricl, Sabrina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593551/
https://ncbi.nlm.nih.gov/pubmed/28915580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19341
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