Molecular and functional characterization of a new 3′ end KIT juxtamembrane deletion in a duodenal GIST treated with neoadjuvant Imatinib

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. GISTs express the receptor tyrosine kinase KIT, and the majority of GISTs present KIT gain-of-function mutations that cluster in the 5′ end of the receptor juxtamembrane domain. On the other...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Perfetti, Vittorio, Laurini, Erik, Aulić, Suzana, Fermeglia, Maurizio, Riboni, Roberta, Lucioni, Marco, Dallera, Elena, Delfanti, Sara, Pugliese, Luigi, Latteri, Francesco Saverio, Pietrabissa, Andrea, Pricl, Sabrina
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593551/
https://ncbi.nlm.nih.gov/pubmed/28915580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19341
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