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Are two better than one? A novel double‐mutant KIT in GIST that responds to Imatinib
Gastrointestinal stromal tumors carry in about 85% of the cases activating mutations in KIT gene. Generally only one KIT mutation is found in primary tumors and the majority of mutations affecting KIT exon 11 is sensitive to Imatinib. We report upon a GIST case harboring a double‐mutant KIT gene at...
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Publicado no: | Mol Oncol |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528426/ https://ncbi.nlm.nih.gov/pubmed/23567324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.02.019 |
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