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Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo
Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with poor prognosis and limited therapeutic options. The incidence of IPF increases with age, and ageing-related mechanisms such as cellular senescence have been proposed as pathogenic drivers. The lung alveolar epithelium represents...
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| Veröffentlicht in: | Eur Respir J |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
European Respiratory Society
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5593348/ https://ncbi.nlm.nih.gov/pubmed/28775044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.02367-2016 |
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