Ligand-guided selection of aptamers against T-cell Receptor-cluster of differentiation 3 (TCR-CD3) expressed on Jurkat.E6 cells

We recently introduced a screening technology termed ligand-guided selection, (LIGS), to selectively identify target-specific aptamers from an evolved cell-SELEX library. Cell-SELEX utilizes a large combinatorial single-stranded oligonucleotide library and progressively selects DNA ligands against w...

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Udgivet i:Anal Biochem
Main Authors: Zumrut, Hasan E., Ara, Mst. N., Maio, George E., Van, Nabeela A., Batool, Sana, Mallikaratchy, Prabodhika R.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593316/
https://ncbi.nlm.nih.gov/pubmed/27519622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2016.08.007
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