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Systematic optimization and modification of a DNA aptamer with 2′-O-methyl RNA analogues
Nucleic acid aptamers (NAAs) are short synthetic DNA or RNA molecules that specifically fold into distinct three-dimensional structures able to specifically recognize a target. While NAAs show unprecedented promise in a variety of applications, including sensing, therapeutics and diagnostics, one ma...
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| Publicado no: | ChemistrySelect |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716488/ https://ncbi.nlm.nih.gov/pubmed/29226219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/slct.201700359 |
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