Structural optimization of an aptamer generated from Ligand-Guided Selection (LIGS) resulted in high affinity variant toward mIgM expressed on Burkitt’s lymphoma cell lines

Aptamers are synthetic, short nucleic acid molecules capable of specific target recognition. Aptamers are selected using a screening method termed Systematic Evolution of ligands by Exponential enrichment (SELEX). We recently have introduced a variant of SELEX called “LIgand-Guided-Selection” (LIGS)...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biochim Biophys Acta
Päätekijät: Zümrüt, Hazan E., Batool, Sana, Van, Nabeela, George, Shanell, Bhandari, Sanam, Mallikaratchy, Prabodhika
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593314/
https://ncbi.nlm.nih.gov/pubmed/28363693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2017.03.020
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia