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Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation

Tauopathies are a class of neurodegenerative diseases, including Alzheimer’s disease, frontotemporal dementia and progressive supranuclear palsy, that are associated with the pathological aggregation of tau protein in neurofibrillary tangles (NFT). Studies have characterized tau as a “prion-like” pr...

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Bibliografiske detaljer
Udgivet i:Neurobiol Dis
Main Authors: Reilly, Patrick, Winston, Charisse N., Baron, Kelsey, Trejo, Margarita, Rockenstein, Edward M., Akers, Johnny C., Kfoury, Najla, Diamond, Marc, Masliah, Eliezer, Rissman, Robert A., Yuan, Shauna H.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593133/
https://ncbi.nlm.nih.gov/pubmed/28610892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.06.005
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